Comparative effectiveness of oral diabetes drug combinations in reducing glycosylated hemoglobin

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Comparative effectiveness of oral diabetes drug combinations in reducing glycosylated hemoglobin.

AIMS To provide evidence on the comparative effectiveness of oral diabetes drug combinations. METHODS We performed a retrospective, observational cohort study of glycosylated hemoglobin change in outpatients newly exposed to dual- or triple-drug oral diabetes treatment. RESULTS Adjusted response to a second drug added to metformin ranged from 0.85 to 1.21% glycosylated hemoglobin decline. R...

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Glycosylated Hemoglobin: The Importance in Management of Type 2 Diabetes

Type 2 diabetes is a major public health problem with high and increasing prevalence, morbidity and mortality. The association between diabetes and microvascular and macrovascular complications is well known besides, tight glycemic control is a necessity. HbA1C has clinically been used since 1980s as a gold standard for monitoring glycemic control and predicting of diabetic complications. The p...

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Comparison of the Effectiveness of Compassion-based Therapy and Acceptance-based Therapy and Commitment to Self-care Behavior and Glycosylated Hemoglobin in Patients With Type 2 Diabetes

Background: Diabetes is one of the most common diseases affecting peoplechr('39')s mental health and the body. Therefore, psychological interventions seem necessary to solve the problems caused by this disease.  Objective: The present study aimed to compare the effectiveness of Compassion-focused Therapy (CFT) and Acceptance and Commitment Therapy (ACT), and commitment to self-care behavior an...

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Glycosylated hemoglobin assay and oral glucose tolerance test compared for detection of diabetes mellitus.

We compared the oral glucose tolerance test (I) as evaluated by six commonly used scoring methods and total glycohemoglobin assay (II) with respect to their value in the diagnosis of diabetes mellitus. Depending on the evaluation method used for I, 16.7 to 64.3% of those subjects diagnosed as diabetic or borderline by this test were judged to be normal by II. The best agreement was between II a...

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BACKGROUND In persons with diabetes, chronic hyperglycemia (assessed by glycosylated hemoglobin level) is related to the development of microvascular disease; however, the relation of glycosylated hemoglobin to macrovascular disease is less clear. PURPOSE To conduct a meta-analysis of observational studies of the association between glycosylated hemoglobin and cardiovascular disease in diabet...

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ژورنال

عنوان ژورنال: Journal of Comparative Effectiveness Research

سال: 2014

ISSN: 2042-6305,2042-6313

DOI: 10.2217/cer.13.87